Welcome to Renagen: Pioneering RNA-Targeted Drug Discovery

At Renagen, we're leveraging deep learning to unlock the potential of RNA-targeted small molecule drug discovery. Our innovative approach aims to overcome traditional challenges in predicting RNA structures, offering new pathways to treat diseases at their genetic roots.


What is RNA and what does it have to do with drug discovery?

RNA stands for ribonucleic acid, a crucial molecule that carries genetic blueprints from DNA to guide protein synthesis in cells. Its involvement doesn't stop at protein creation; RNA also plays a pivotal role in controlling which genes are turned on or off in our cells, making it an attractive target for new drug therapies. By designing drugs that can specifically target RNA molecules, we open up new possibilities for treating diseases at the genetic level, offering a broader range of drug discovery opportunities.


So why does it not exist already?

The challenge in leveraging RNA for drug discovery lies in the complexity of predicting RNA structures. RNA molecules are notoriously difficult to model due to their dynamic and flexible nature. Traditional computational methods have struggled because they can't accurately capture the intricate ways RNA folds.


How do YOU plan to solve this problem?

We are developing a deep learning model (think AlphaFold but for RNA!) that can predict RNA secondary structure and RNA-ligand interactions with high accuracy. By integrating two types of learning — end-to-end and geometrical restraint—our AI tool can potentially predict RNA structures with unprecedented precision, providing a solid foundation for drug discovery and other scientific inquiries.


Awesome! Do you have a product already?

We are currently in the process of training our model and looking forward to showcasing our v1 model soon. Stay tuned!


Can you tell us more about yourselves?

We are a small team of passionate scientists and engineers from MIT and Northeastern University. Our team members have diverse backgrounds in computational biology, machine learning, and drug discovery.


How can I be part of your team?

While we are not actively hiring at the moment, we are always looking for passionate individuals who share our vision. If you are interested in joining our team, please send us your resume at hiring[AT]renagen[DOT]net.

We are also looking for investors who are interested in supporting our mission. If you are interested in investing in our company, please send us an email at ir[AT]renagen[DOT]net.

For any other inquiries, please reach out to us at ceo[AT]renagen[DOT]net.